For eye doctors

Limbal and conjunctival findings in scleral lens wearers

A guide to the landing zone and limbal signs you will see in scleral lens patients, which are expected, which point to a fit problem, and which need more than a refit.

By the Scleral Lens Team · Updated October 2, 2026 · 13 published sources cited

The short answer

A scleral lens bears on the conjunctiva, so some landing zone change is expected: a faint impression ring after removal usually fades within hours. Sectoral or circumferential blanching during wear with rebound hyperemia after removal, edge impingement, quadrant staining, or limbal staining point to a fit problem that the fitter can usually correct with design changes. Imaging studies show measurable conjunctival vascular and thickness changes under the landing zone, of uncertain long-term significance. Limbal compromise in eyes with limbal stem cell deficiency needs closer attention.

Key points

  • Only 5.7% of 140 scleras mapped with a scleral topographer were essentially spherical, which is why toric and quadrant-specific landing zones exist.
  • A compression ring without blanching or staining is generally benign and fades within hours of removal.
  • Blanching during wear followed by rebound hyperemia after removal points to mechanical compression.
  • In 27 eyes with limbal stem cell deficiency, LSCD stage worsened in 44.4% during scleral lens wear, with imaging evidence of limbal compression in the eyes studied.
  • Pingueculitis occurred in 1.3% of eyes in a keratoconus series.

Why the landing zone shows changes

A scleral lens is meant to vault the cornea and limbus and land evenly on conjunctiva over the sclera, without compression, impingement, or edge lift.[2] The sclera rarely makes that easy. Of 140 eyes mapped with a scleral topographer, only 5.7% had a primarily spherical sclera; 28.6% were regularly toric and the rest had asymmetric or irregular patterns, with the nasal sclera generally flatter.[2] That asymmetry is why toric, quadrant-specific, and impression-based landing zones exist, and why the findings below are often sectoral.

Lenses also settle into the conjunctiva over the first hours of wear, which a 2025 review attributes mainly to tissue compression under the landing zone. If too little clearance was built in, settling can produce limbal or corneal bearing.[3]

Findings, what they mean, and who acts

Finding Usual meaning First response
Faint impression ring after removal, no blanching or staining Expected compression, usually benign Note it
Blanching during wear, rebound hyperemia after removal Landing zone compression Fitter
Edge digging into conjunctiva, staining at edge Impingement Fitter
Fluorescein pooling under the edge, bubbles entering Edge lift Fitter
Tissue drawn under the lens at the limbus Conjunctival prolapse Fitter
Limbal staining, limbal haze, or new vessels Limbal bearing or hypoxia Fitter, promptly
Inflamed pinguecula under the landing zone Pingueculitis You treat; tell fitter
Conjunctival cyst at the edge Impingement microtrauma Fitter; you if excision needed

Compression and blanching

What you see: whitening of conjunctival vessels, circumferential or in a sector, at the inner or outer edge of the landing zone, sometimes with hyperemia just beyond the edge. After removal, an impression ring.[3]

How to read it: the 2025 review treats blanching during wear followed by rebound hyperemia in the same area after removal as pointing to mechanical compression. An impression ring alone, without blanching or staining, is generally considered benign and typically resolves within a few hours. Some patients have a hypersensitive conjunctiva that reddens with any manipulation, which complicates the picture.[3] Persistent redness and discomfort from compression can shorten wear time and lead to intolerance.[3]

What the fitter can change: flattening the peripheral curves, or moving to a toric or quadrant-specific landing zone to match scleral asymmetry.[3] A 2026 case series of poorly fitted lenses showed that design changes can let patients resume wear, and advised reassessing both fit and underlying disease at scheduled intervals.[12]

What imaging shows under the landing zone

Several small studies have measured changes that the slit lamp may not show. Their long-term clinical significance is unknown.

  • OCT angiography, 13 wearers of spherical mini-scleral lenses: inferior conjunctival vessel density under the lens fell after 1 hour of wear compared with at least 8 hours lens-free, and clinician-graded impingement on slit photographs correlated with the OCT-A findings in three quadrants.[4]
  • Functional slit lamp imaging, 19 eyes over 3 hours: conjunctival morphology under the landing zone changed progressively during wear, with associated changes in blood flow and vessel density.[5]
  • Long-term wear, 17 keratoconus eyes: conjunctival-episcleral thickness was lower than in healthy controls, especially superiorly and inferiorly, and superior thinning correlated with years of wear; scleral thickness itself did not differ.[6]
  • Single-subject pilot: with increasing sagittal height, OCT-A showed perilimbal vascular interruption of 0%, 25%, and 75%.[7]

Impingement, edge lift, and staining

Impingement is the lens edge pressing into conjunctiva; edge lift is the opposite, with fluorescein pooling under the edge and sometimes bubbles entering the reservoir. Compression and impingement can occur together, and a lens can lift in one meridian while aligning well in the opposite one.[2] The 2022 review recommends assessing alignment in all gaze positions and again after several hours of wear, once the lens has settled.[2]

Conjunctival staining in one quadrant is worth recording by location for the fitter. Removal technique matters too: a 2025 review notes that placing the plunger too close to the lens center is a common error that can cause blanching, impingement, hemorrhage, and corneal or conjunctival staining.[3]

Conjunctival inclusion cyst: a case report describes an epithelial inclusion cyst of the bulbar conjunctiva from chronic edge impingement, managed with a lens modification (a MicroVault) rather than surgery. The authors note diameter changes or notches are the more common correction.[8]

Suction: a case report described intracorneal hemorrhage within 4 hours of application and removal training on the first day of wear, in an eye with long-standing keratoconjunctivitis, and framed it as a mechanical complication related to suction between lens and ocular surface.[13]

Pinguecula and pingueculitis

A raised pinguecula under the landing zone is a common reason for a notch or focal vault. In a retrospective keratoconus series of 157 eyes, pingueculitis occurred in 1.3% of eyes.[11] Treat the inflammation as you would in any patient and tell the fitter, who can offload that area.

Corneal surface findings after removal

  • Epithelial bogging: elevated, swollen, waterlogged-looking epithelium after removal, with positive corneal or negative limbal fluorescein staining. Its cause is unknown, and current evidence suggests no long-term harm. Midday removal, rinsing, and reapplication, or a design change, may reduce it.[3]
  • Epithelial bullae: negative-staining areas, often near the limbus, attributed mainly to mechanical compression with a hypoxic contribution. The review advises stopping wear until they resolve, which can take at least a week, then refitting to avoid excess vault and compression.[3]

The limbus

Scleral lenses are meant to clear the limbus entirely. Limbal bearing appears in a 2016 review’s list of findings unique to scleral lens wear.[1] The stakes are highest in limbal stem cell deficiency. In a retrospective series of 27 eyes with confirmed LSCD fitted with scleral lenses, acuity improved in 25.9%, was stable in 48.1%, and fell in 25.9%; LSCD stage improved in 25.9%, was stable in 29.6%, and worsened in 44.4%. Anterior segment OCT and fluorescein angiography in 5 eyes showed limbal compression and delayed filling, and the authors suggest limbal hypoxia may drive worsening.[9]

Across the wider wearer population, a practitioner survey covering 72,605 wearers estimated that 0.20% discontinued wear over one year because of limbal stem cell deficiency.[10] For vessels crossing the limbus, see scleral lenses and corneal neovascularization. For tissue drawn under the lens, see conjunctival prolapse.

Common questions

Is a red ring after removal normal?

A faint impression ring without blanching or staining is generally considered benign and typically fades within a few hours, according to a 2025 review. Blanching during wear with rebound redness in the same place after removal points to compression, which the fitter should address. Some patients have a reactive conjunctiva that reddens with any manipulation, which can make this harder to read.

Who should manage a pinguecula under the landing zone?

Both of you. Treat pingueculitis as you normally would and tell the fitter, who can relieve that area with a notch, a focal vault, or a quadrant-specific landing zone. In a keratoconus series of 157 eyes, pingueculitis occurred in 1.3%.

Can poor removal technique cause these findings?

Yes. A 2025 review describes plunger placement too close to the lens center as a common error that can cause conjunctival blanching, impingement, hemorrhage, and corneal or conjunctival staining. A subconjunctival hemorrhage after removal is worth mentioning to the fitter so technique can be checked.

Are scleral lenses safe for eyes with limbal stem cell deficiency?

They are used for it, and in one series vision improved or stayed stable in most eyes. But LSCD stage worsened in 44.4% of 27 eyes, and imaging in the eyes studied showed limbal compression and delayed fluorescein filling. The authors recommend close monitoring of fit in these compromised eyes.

Keep reading

Conjunctival prolapse and scleral lenses

Conjunctival prolapse is limbal or perilimbal conjunctiva drawn into the space under a scleral lens. It is common: in an OCT study of 10 healthy adults, 8 showed it at least once during 90 minutes of wear, most often nasally, and its height tracked how far the lens settled at the limbus. Reviews describe it as usually benign but capable of causing discomfort or, if extensive, blocking vision. It is a fit issue to send back to the fitter, who may change the edge, landing zone, or limbal clearance.

Scleral lens complications to watch for

Most scleral lens problems are lens-related rather than physiological: broken lenses, deposits, poor wetting, and midday fogging. Physiological complications are less common and include conjunctival changes at the landing zone, corneal edema (higher risk in grafts), hydrops in keratoconus, and, rarely, microbial keratitis. Infection, rejection, and acute hydrops need same-day care; fit-related findings go back to the fitter.

Scleral lenses and corneal neovascularization

New corneal vessels in a scleral wearer usually point to hypoxia, limbal bearing, or a tight landing zone, or to the underlying disease. A practitioner survey estimated that 0.53% of wearers stopped lens wear in a year because of neovascularization, so it is uncommon but real. Document vessels at baseline, report new or advancing vessels to the fitter promptly, and treat inflammation. In severe surface disease, small case series report regression of existing vessels with PROSE, including when used to deliver topical bevacizumab.

What the fitter sends back

A complete report gives the final lens parameters and material, acuity in the lens, how the lens sits on the eye (central and limbal clearance, landing zone, any blanching or impingement), the corneal and conjunctival findings after wear, the care products and wear schedule, the follow-up plan, and anything the fitter needs you to act on. Expect an initial note after the evaluation and a final report once the fit is complete.

Sources

  1. Walker MK, Bergmanson JP, Miller WL, Marsack JD, Johnson LA. Complications and fitting challenges associated with scleral contact lenses: a review. Cont Lens Anterior Eye. 2016;39(2):88-96. doi:10.1016/j.clae.2015.08.003 pubmed.ncbi.nlm.nih.gov
  2. Macedo-de-Araújo RJ, Fadel D, Barnett M. How can we best measure the performance of scleral lenses? Current insights. Clin Optom (Auckl). 2022;14:47-65. doi:10.2147/OPTO.S284632 pubmed.ncbi.nlm.nih.gov
  3. Rodriguez-Garcia A, Jimenez-Perez JC, Ruiz-Lozano RE, et al. Scleral lenses and PROSE: indications, complications, and future challenges. Med Hypothesis Discov Innov Ophthalmol. 2025;14(3):73-106. doi:10.51329/mehdiophthal1525 pubmed.ncbi.nlm.nih.gov
  4. Alipour F, Abdi P, Asadigandomani H, Khodaparast M, Montazeriani Z, Sajedi M. Investigating the vascular structure of the conjunctiva in patients using spherical mini-scleral contact lenses utilizing OCT-A imaging. Sci Rep. 2025;15(1):4759. doi:10.1038/s41598-025-89159-x pubmed.ncbi.nlm.nih.gov
  5. Fan X, Huang H, Shi C, Jiang J, Lu F, Shen M. Changes in bulbar conjunctival microcirculation and microvasculature during short-term scleral lens wearing and their associated factors. Cont Lens Anterior Eye. 2024;47(5):102159. doi:10.1016/j.clae.2024.102159 pubmed.ncbi.nlm.nih.gov
  6. Bolac R, Yıldız MB, Alpogan O, Un Y, Mangan MS. The effect of extended periods of mini-scleral lens wear on the conjunctival/episcleral and scleral thickness. Cont Lens Anterior Eye. 2025;48(1):102289. doi:10.1016/j.clae.2024.102289 pubmed.ncbi.nlm.nih.gov
  7. Gimenez-Sanchis I, Palacios-Carmen B, García-Garrigós A, Cantó-Vañó J, Pérez-Ortega AJ, Piñero DP. Anterior segment optical coherence tomography angiography to evaluate the peripheral fitting of scleral contact lenses. Clin Optom (Auckl). 2018;10:103-108. doi:10.2147/OPTO.S164454 pubmed.ncbi.nlm.nih.gov
  8. Sherman SW, Cherny C, Suh LH. Epithelial inclusion cyst of the bulbar conjunctiva secondary to scleral lens impingement managed with a MicroVault. Eye Contact Lens. 2020;46(6):e56-e58. doi:10.1097/ICL.0000000000000659 pubmed.ncbi.nlm.nih.gov
  9. Bonnet C, Lee A, Shibayama VP, Tseng CH, Deng SX. Clinical outcomes and complications of fluid-filled scleral lens devices for the management of limbal stem cell deficiency. Cont Lens Anterior Eye. 2023;46(1):101528. doi:10.1016/j.clae.2021.101528 pubmed.ncbi.nlm.nih.gov
  10. Schornack MM, Nau CB, Harthan J, Shorter E, Nau A, Fogt J. Survey-based estimation of corneal complications associated with scleral lens wear. Eye Contact Lens. 2023;49(3):89-91. doi:10.1097/ICL.0000000000000972 pubmed.ncbi.nlm.nih.gov
  11. Fuller DG, Wang Y. Safety and efficacy of scleral lenses for keratoconus. Optom Vis Sci. 2020;97(9):741-748. doi:10.1097/OPX.0000000000001578 pubmed.ncbi.nlm.nih.gov
  12. Nau CB, Nau AC, Fogt JS, Shorter ES, Harthan JS, Schornack MM. Complications of poorly fitted scleral lenses and approaches to continued wear. Eye Contact Lens. 2026;52(10):432-435. doi:10.1097/ICL.0000000000001306 pubmed.ncbi.nlm.nih.gov
  13. Trinh J, Bernhisel AA, Nau CB, Schornack MM. Intracorneal hemorrhage associated with scleral lens wear. Eye Contact Lens. 2025;51(10):450-453. doi:10.1097/ICL.0000000000001215 pubmed.ncbi.nlm.nih.gov

Last updated October 2, 2026. Found an error or a newer study? Let us know and we'll correct the page.