What a fenestration is
A scleral lens holds a pool of saline against your cornea and seals gently on the white of your eye. That seal is part of what makes the lens stable, but it also limits how much fresh tear fluid flows in behind it. Tear exchange matters because fresh tears carry oxygen to the cornea and wash out waste and debris.[1]
Fitters have several ways to increase tear exchange: fitting the landing zone slightly flatter, adding channels on the back surface, or adding fenestrations.[1] A fenestration is a tiny hole through the lens, usually placed over the limbus. Fenestrations have been used since the glass scleral lenses of the 1940s, but few studies had measured their effect until recently.[1]
A common layout is three holes spaced evenly around the lens, so at least one stays within the eye opening if the lens rotates. Reported sizes range from 0.1 to 2 mm.[1] Holes or grooves can also reduce the suction that makes some small lenses hard to remove.[6]
What the recent studies found
A research group in Australia has published a series of short studies on fenestrated scleral lenses, all in healthy adults with normal corneas.
- Corneal swelling. Twenty healthy adults wore the same lens with and without three 1 mm fenestrations for 3 hours each. Central corneal swelling was 39% lower on average with the fenestrated lens. The benefit appeared whether or not an air bubble was present behind the lens.[1] An earlier study using a single much smaller hole (0.3 mm) in nine people found less swelling at the edge of the cornea near the hole, but no clear difference in the center.[4]
- Debris in the fluid. In the same 20 adults, debris in the fluid reservoir built up over 3 hours with both lenses, but more with the non-fenestrated lens, roughly 2 to 5 times more depending on the measure used (only one of the two measures reached statistical significance).[2]
- Tear flow. A pilot study of nine people wearing a lens with one 0.3 mm hole found two patterns: some eyes had low tear flow and some had high flow. The low-flow group had more corneal swelling, though the difference wasn’t statistically significant.[3]
These are useful early results, but they come from short wear in young, healthy eyes. The authors say longer studies in people with eye disease are needed.[2]
The trade-off: bubbles
Holes let air in as well as tears out. In the swelling study, half the participants wore the fenestrated lens with a small, moving bubble at the edge that didn’t affect their vision.[1] The authors note from clinical experience that larger or more numerous fenestrations make it more likely that a large bubble gets in and drifts toward the center of vision.[1] A bubble over the center blurs vision and leaves that part of the cornea without fluid.
Who might be offered one
Reducing corneal swelling matters most when the cornea can’t pump fluid out well, for example after a corneal transplant. Fenestrations are one of several tools for lowering oxygen stress, along with more oxygen-permeable materials, thinner lenses, less fluid between lens and cornea, and limiting wear time.[5] Your fitter may suggest a fenestrated design if your cornea swells, if debris clouds your lens during the day, or if a lens is hard to remove. Ask what they’re aiming to fix and how you’ll know if it’s working. For more on swelling, see do scleral lenses change the shape of your cornea?
Common questions
Will a fenestrated lens stop my midday fogging?
It might help some people, but that hasn't been shown yet. A small study in healthy eyes found less debris build-up behind fenestrated lenses over three hours. Whether that translates into less fogging over a full day, in people with dry eye or other conditions, still needs to be studied.
Do I fill a fenestrated lens differently?
Follow your fitter's instructions for your specific lens. Because fluid can escape through the holes and air can get in, your fitter may give you specific tips for filling and inserting it.
Is a bubble under a fenestrated lens a problem?
A small bubble at the edge that doesn't affect your vision or comfort may be acceptable, and in research studies such bubbles were tolerated. A bubble that drifts over the center of your vision, or that causes discomfort, is something to report to your fitter.
