How diabetes affects the cornea
Most people know diabetes can damage the retina. Fewer know it affects the cornea too. A 2019 review describes people with diabetes as commonly having damage to the cornea’s protective surface barrier, abnormal wound healing, a fragile surface layer, loss of corneal nerves and sensitivity, and a higher overall risk of bacterial and fungal infections.[1] An earlier review adds changes in tear chemistry and tear production, and changes to the cornea’s inner cell layer.[2]
Diabetes is also one of the systemic causes of neurotrophic keratopathy, a condition in which the cornea loses feeling and heals poorly.[3] It’s listed among the systemic risk factors for corneal ulcers as well.[5]
What that means for scleral lens wear
Infection risk: the evidence is mixed. One landmark study from 1989 found diabetes was the only systemic disease linked to a higher risk of contact lens-related corneal infection, but later studies have disagreed with each other.[1] The 2019 review concluded there are inherent risks with contact lens wear in diabetes, and that little evidence yet shows how large the added risk is.[1] The 2012 review notes that studies of modern lenses suggest contact lenses can be a workable option for people with diabetes.[2] None of this research was specific to scleral lenses.
Reduced feeling can hide early warning signs. Pain and discomfort are among the warning signs the FDA lists for contact lens problems.[6] If diabetes has reduced your corneal sensitivity, you may not feel a problem as early. Watch for the other signs on that list too: blurred vision, unusual redness, discharge, and unusual sensitivity to light.[6] If in doubt, take the lens out and call.
The cornea’s inner layer matters. A 2025 review lists diabetes among the conditions that can lower the number of endothelial cells, the cells that keep the cornea clear, and treats a low count as a relative or absolute reason not to wear a scleral lens, depending on severity.[4] Ask whether your endothelium has been checked before fitting.
Fitters weigh the whole picture. The 2019 review advises fitters to consider how long you’ve had diabetes, how well it’s controlled, whether you have retinopathy, and your overall health.[1] Bring an up-to-date list of your medications and diagnoses to your fitting.
Scleral lenses as treatment for diabetic corneal damage
In some people with diabetic neurotrophic keratopathy, scleral lenses are part of the treatment rather than a risk. A 2025 review describes scleral lenses as having a protective and therapeutic role, including for persistent surface defects, and illustrates it with a patient whose diabetic neurotrophic keratopathy was treated with a scleral lens.[3] That kind of use happens under close medical supervision. See scleral lenses for neurotrophic keratitis.
Hands and handling
Peripheral neuropathy is one of the conditions that can make inserting and removing scleral lenses harder.[4] If your fingertips are numb or less precise, these guides may help: shaky hands and inserters and removers.
Good habits matter more
Infection prevention habits apply to everyone, but they carry extra weight if your cornea heals slowly. The FDA’s advice includes rubbing and rinsing lenses as directed, never topping off solution, keeping all water away from lenses, and replacing your case regularly.[6] Never sleep in scleral lenses: overnight wear is considered an absolute contraindication.[4] See cleaning and disinfecting and are scleral lenses safe?.
Common questions
Does my blood sugar control matter for wearing scleral lenses?
It's one of the things fitters are advised to consider, along with how long you've had diabetes, whether you have retinopathy, and your general health. Research on exactly how glucose control affects contact lens risk is mixed. Tell your fitter about your diabetes and any changes in your treatment, and keep your diabetes care team informed that you wear lenses.
Can scleral lenses help diabetic retinopathy or macular edema?
No. Those affect the retina at the back of the eye. A scleral lens only changes the front surface. Treatment for retinopathy comes from your eye doctor or retina specialist.
I have neuropathy in my hands. Will that make lenses harder?
It can. Peripheral neuropathy is one of the conditions known to make inserting and removing scleral lenses harder. Tools such as lighted inserters, stands and one-finger applicators can help, and your fitter can tailor your training.
